mme_hardy: White rose (Default)
[personal profile] mme_hardy
Three different preventative drugs for migraine are in late-stage trials and doing well. This is a big damn deal. There are drugs that are abortives -- once you start feeling migraine symptoms, you take them to drastically reduce those symptoms -- but all the preventatives are off-label for something else.

To give you some idea, the preventatives I take are:
  • Lyrica (Federally approved for seizures, neuropathic pain, and fibromyalgia)
  • Botox (Federally approved for torticollis, lots of other clenched-muscle conditions, and various kinds of cosmetic uses)
In the past I have tried beta and calcium-channel blockers (high blood pressure), multiple anti-epileptics, and IIRC one antihistamine that had to be special-ordered from Canada.

The migraine-specific triptan drugs, when they were introduced, were a revolution: instead of blunting the pain you were short-circuiting the migraine cycle.   I have hopes that one of these three drugs will be a similar game-changer for prevention.  Fingers crossed.

In the meantime, I'm overdue for a Botox treatment; will schedule tomorrow.



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